Showing posts with label medicine. Show all posts
Showing posts with label medicine. Show all posts

Saturday, July 21, 2012

We All Spend Time As A Shadow

I leave my apartment and hop in the car, already feeling a little drowsy. It's 10:30 pm, and I'm heading to work. In order to satisfy a requirement for an internship, I scheduled two ED shadowing shifts back to back, starting at 11pm and going till 7am. I took two shifts previously from 6pm to 2am, but this was different. Going to work in the middle of the night feels unnatural, though the commute is pretty good. I arrive at the hospital, carrying my coffee-filled thermos (essential), ready for the night shift.

So, you want to be a doctor. Fantastic (although if I had a nickel for every time I heard that, I wouldn't be taking out so many loans for med school). What does a doctor do? If you answered "Helps people" you are probably a freshman with good intentions but much naïveté. If you chose "Paperwork" or "Sitting at a computer" you probably have a little more experience. If you said "Inflict pain and interrupt frequently" you are probably a patient. Most people have a general idea of what physicians do, but they lack the important day-to-day details. Medicine is fairly romanticized thanks in large part to shows like ER, House, or Grey's Anatomy, and the many that came before it. Watching people put in orders, review charts, wait for labs, or conduct rounds does not make for very interesting TV (to the general public at least). Thus we arrive at our stereotypical freshman pre-med, gunning for med school without any conception of what physicians actually do. This is where shadowing comes in.

The ED is arranged like a giant horseshoe, the interior being the nurses' and physician's stations and the exterior being the patient rooms. I set my coffee down and put my snack in the mini-fridge (god help you if you fail to bring snacks). I greet Dr. S. and we begin the night. Dr. S. is very mild mannered and speaks calmly (ER docs tend to come from both ends of the spectrum, calm and manic). It is a typical night at the ER; abdominal pain is coming at us from every direction and shows no sign of letting up. Not too far into the shift, an elderly woman arrives by EMS. She was unconscious and had some dried blood on her head, suspicious for a fall. She was weakly responsive to pain, but no spontaneous movement or sounds. She got the usual 'ER Special' consisting of IVs, blood tests, and cardiac monitoring. She would almost certainly be admitted. Neurology would be consulted as soon as possible. Several hours later, her daughter came running out of the room, shouting for help; the patient was having a seizure. After a tense minute or two of not being able to locate any nurses or Dr. S. (he is the only physician on at this point), we stream into the room to assess the situation. The patient has stopped seizing at the moment, but is now not breathing. Her heart rate plummets. Quickly, a nurse starts to bag her, and Dr. S. makes the decision to intubate. Respiratory is paged, and a nurse prepares anti-convulsants. Finally, she's stabilized, and we all go back to work. No rest for the weary.


Shadowing is exactly as it sounds: the student follows the physician like a shadow, in order to observe. However, unlike a shadow, you will constantly be in the way, and you can/might be allowed to ask questions. Medical students are expected to ask questions, even if they end up being forced to answer their very own questions and ultimately being chastised for not knowing the answer (doesn't seem fair does it). It is extremely useful though, because you gain firsthand knowledge of how a typical day/shift goes. For example, I was shadowing an ER doc, and for the first 2-3 hours, we didn't see one patient. Labs were backed up and beds were full, so we just sat on our asses until it cleared out a bit. You do get to see procedures and patients (especially in surgery), but the little things are actually the most important. Adcoms want to see that you know what you're in for; the fairy-tale can be your motivation, but you better be prepared for the reality.

Around 5am or so, Dr. S. are seeing a patient about back pain when the intercom clicks on. "All help to triage stat!" the nurse shouts (first time I heard stat used in a serious context). Dr. S. is not phased, and continues to interview the patient. Seconds later, "Physician to triage!" Dr. S. sighs, apologizing to the patient, and we head down the hall to the waiting room (slowly I might add). Before we get there, two beds complete with patients come flying around the corner, pushed by a couple personnel. Both patients were stabbed at a party and had just walked in the front door. Minutes later, a third patient comes in and is wheeled back to an empty bed. The ED goes into lock-down, police are called, vitals and IVs are started, and ambulances are called to transfer the patients (the hospital is not a trauma facility). Shortly after our three stab victims arrive, a code blue goes out over the intercom. The physician covering the wards, Dr. P., is currently in the ED, and Dr. S. is not sure if she's even ACLS certified. Dr. S. and his scribe take off after her with the code box, and I am tasked with getting vitals from the patients. They all appear to be in discomfort, but one looks very pale and is shaking (effects of epinephrine). Dr. S. and his now disheveled looking scribe (CPR will do that to you) return, and the patients are transferred.


So, shadowing is important, an unwritten requirement of medical school. But how do you go about it? I was lucky; I got an internship through the university that handled the initial contact. For those less fortunate, I would suggest asking around the hospital if you volunteer at one. Academic medical centers are probably the best choice because they will be used to having medical students around. Ask your friends too. I came from a completely non-medical family, so I was at a bit of a disadvantage. Many of my friends had physician parents or grandparents, so they became a great source of knowledge. There are lots of guides pertaining to shadowing though, so just search SDN or Google for more in depth advice. You don't have to rack up hours and hours of shadowing, but spend one or two full shifts per specialty. It helps to get some variety as well, but even one experience is better than none. Don't forget to have fun, but make sure you reflect on your experiences too. If you really can't see yourself living that life, it might be time to switch paths. That's what shadowing is for. It wipes away some of the glamour, exposing the realism of clinical practice. It disenchants, leaving only the most dedicated behind to finish the journey to medical school.

Sunday, July 15, 2012

Know The Difference: Heart Attack vs Cardiac Arrest

Welcome to the second installment of "Know the Difference," a series which seeks to clear up common medical misnomers. This week, we're tackling a one of the most prominent naming errors on television (and by extension, the public). The scene is a hospital room, with the patient lying in the bed looking quite unhappy and ill. In walk our doctors, who bear an uncanny resemblance to team featured on House. They chat with the patient briefly, exchange some comical banter with each other, and then the patient takes a turn for the worse. The camera pans up to the cardiac monitor, which shows a complete asystole (flat line). Everyone springs dramatically into action, but one of the doctors commits a medical student faux paus. "She's having a heart attack!" he exclaims, sending a brief jolt of pain to the frontal lobes of the clinical staff watching at home.

So what happened? Basically the hotshot doctor was confusing two conditions, heart attack and cardiac arrest. And since they are treated very differently, it is kind of a big deal to get it right. So how do you tell one from the other?

A cardiac arrest (CA) occurs when the heart is no longer pumping blood. This is determined clinically by checking for a pulse. If it is absent, congratulations; you now have a genuine emergency on your hands. When the heart stops pumping blood, oxygen and nutrients cannot circulate through the body, and waste begins to build up. Without intervention, CA is fatal in a matter of minutes (predominantly due to the lack of oxygen)(1). CA is treated differently depending on the cause and EKG interpretation. For instance, the most common one seen on TV is asystole:

Asystole. Note no discernible waves. Courtesy of wikipedia.
This is also the most common rhythm seen in Out-of-Hospital arrests(2). Asystole has a number of causes, some reversible some not. Typically, this rhythm is seen after prolonged pulselessness, so the prognosis is grim. The treatment usually involves reversing the underlying condition (toxicity, tamponade, tension pneumo, etc). What it does not involve is electrical shocks. Asystole is not a shockable rhythm. So, while making for very good television, our team of doctors would not be doing any good with the defibrillator in the typical case. Ventricular fibrillation (V-fib or VF) on the other hand, is shockable, even though it may not look like an abnormal rhythm to the untrained eye.
V-fib. Only random waveforms. Also courtesy of wikipedia.
VF is a pulseless rhythm where the heart is contracting randomly, out of sync. 

A heart attack (MI) is also a serious condition, but does not lead to death per se. An MI occurs when blood flow to the heart is reduced, classically causing chest pain (angina) and dyspnea(2). The reduction of blood flow is usually due to a narrowing in one or more of the coronary arteries. Thus, the primary intervention is to open the arteries back up (PCI) or bypass blocked portions (CABG). The main difference between MI and CA is that cardiac arrest is a complication of an MI. If the blood flow is cut off for too long, heart muscle (myocardium) will die. This can lead to arrhythmias or heart failure, which may lead to death. The EKG of a person having a heart attack can vary substantially, but here are some examples of anterior MIs.

Summary
CA: No pulse, heart is not pumping blood. Rapidly fatal. Treatment (resuscitation) depends on the rhythm appearance.
MI: Reduced blood flow to the heart via the coronary arteries. Muscle death may impair normal function of the heart and lead to death.

So the next time you're watching House or Gray's Anatomy (or ER for the slightly older readers), keep an eye on that monitor and get ready to call those actors out on their mistakes!

Sources
1.CPR - adult. PubMed Health. 2011. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001083/. Accessed July 15, 2012.
2. Mader TJ, et al. Out-of-hospital cardiac arrest outcomes stratified by rhythm analysis. Resuscitation (2012), http://dx.doi.org/10.1016/j.resuscitation.2012.03.033.
3. Heart Attack. PubMed Health. 2011. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001246/. Accessed July 15, 2012.

Friday, June 29, 2012

Apparently I Have An Opinion On Health Care Too!

If you've turned on your TV, glanced at a newspaper, or checked your Facebook in the past 24 hours, you are probably aware of the US Supreme Court ruling on the PPACA (the healthcare reform signed into law back in March 2010). If you're interested in the specifics, you need only google "PPACA" or something of the sort, and you will be inundated with results about what the law entails. In super brief form, it adds several provisions designed to make sure everyone has access to healthcare, as well as means to fund these provisions. One method of funding comes from the "Individual Mandate" (IM), which requires individuals to obtain health insurance or pay a fine/penalty/tax (realistically what it's called doesn't matter because the function is the same in each case). More people buying insurance should increase competition in the market and bring down prices because those that use healthcare infrequently can help subsidize those who use it more often. The Supreme Court case was about this mandate, ultimately deciding it was constitutional under Congress's power to tax. Without the IM, the ACA would face challenges on how to fund the rest of its measures, and that would not be good.

So, why is everyone making so much noise about this law? Good question; one that has many answers. First, people are upset because they feel like they shouldn't be obligated to buy health insurance. Understandable, except for the fact that, at some point, every person will use the healthcare system. This is analogous to car insurance: if you drive a car, you are required (in nearly all states) to have insurance. That way, if someone attempts to occupy your location in space and time, you can be sure to be reimbursed for the energy the imparted into your rear bumper. If you are caught without insurance, you face a fine (sound familiar?). "But Liam," you say, "People who don't drive don't need insurance. I don't get sick, so I shouldn't need health insurance!" Unfortunately, not quite, because by virtue of being born as a human being (welcome to the club, 7 billion strong!), you have entered the healthcare market. You may never get in an accident, but you still must have insurance to cover damages. Similarly, you may never get sick, but you must have insurance to pay for services if you do. Essentially, this is designed to work like Social Security, where the old (sick) are supported by the young (healthy). Everyone becomes old at some point, so it is reasonable to collect money from everyone.

Interestingly enough, people seem to favor the provisions in the ACA, such as eliminating pre-existing conditions, but are against the IM and the law as a whole. This sort of amounts to, "we like the benefits, just not the part where we have to pay for it." While an unpleasant realization, there is no avoiding it. Healthcare is really expensive, and it shows no signs of getting cheaper spontaneously. Resources are limited, and if we don't allocate them responsibly, everyone gets screwed. The real trick is figuring out how to cut costs and manage resources while still getting quality healthcare. Originally, the focus was on waste and inefficiency in administrative and clinical settings. EHRs, streamlined billing, new payment models, and evidenced-based medicine can save money by preventing treatments and procedures that have no benefit as well as minimizing overhead costs. However, new estimates suggest that fixing 'waste' won't make up for the increasing expenditures. This doesn't mean we'll ignore all those savings; we just need to make additional changes. 

Additional cuts will come from limiting some services. We will have to start saying no to some procedures and devices in some patients. Expensive imaging studies or surgical procedures may be foregone in favor of clinical diagnoses and alternative therapies. In addition, the new focus will be on preventing chronic diseases rather than attempting to manage existing ones. For example, look at diabetes and heart disease (co-morbidities in many cases too). Diabetes alone was estimated by the ADA to cost us $174 billion (in 2007). Heart disease (which includes HTN, CAD, CVA, and CHF) was estimated to cost us $272 billion (in 2010). Both diseases are highly preventable with lifestyle modifications and supportive drug therapy if necessary.

I suppose my overall point, and I'm not alone in this, is that healthcare reform is necessary and will occur no matter what goes on in government. I think that having the PPACA and IM is an important step in the right direction, but it is only the beginning. Buckle up, because there's a long, tough road ahead.

Edit
Ran across this article just now. Should help clear up some misconceptions and disinformation.
http://www.usatoday.com/news/politics/story/2012-06-29/fact-check-court-health/55927118/1

Citations

Bloche MG. Beyond the “R Word”? Medicine's new frugality. N Engl J Med. 2012;366:1951-1953.
Blumenthal D. Performance improvement in health care — Seizing the moment. N Engl J Med. 2012;366:1953-1955.
Brody H. From an ethics of rationing to an ethics of waste avoidance. N Engl J Med. 2012;366:1949-1951.
Fuchs VR. Major trends in the U.S. health economy since 1950. N Engl J Med. 2012;366:973-977.
Song Z, Landon BE. Controlling health care spending — The Massachusetts experiment. N Engl J Med. 2012;366:1560-1561.

Thursday, June 21, 2012

Know the Difference: Allergy vs Adverse Reaction

A common question, asked at least once at every assessment. It is an important question because it is the difference between taking a drug and getting better, or say, going into anaphylactic shock. Typically, we try to avoid the latter.

However, the responses I've heard to this question indicate to me that there is a crucial misunderstanding about what an allergy is. On several occasions I've heard people say they are allergic to a drug, and when asked what reaction occurred, they respond with nausea or something of the sort. Of course, nausea can be a symptom of an allergic reaction, particularly in anaphylaxis. Usually though, nausea is a side effect of a medication, which is separate from an allergy. Now, time for some science and jargon!

An allergic reaction (Type I Hypersensitivity for those of you so inclined) occurs when IgE, a type of immunoglobulin (antibody), interacts with an allergen. IgE bound to the allergen can then bind to receptors on mast cells, basophils, and eosinophils to stimulate an allergic reaction. Mast cells in particular release large quantities of histamine (along with cytokines and other chemicals), which causes vasodilation as part of the inflammatory response. When vasodilation of the blood vessels in the skin occurs, the affected area will turn redder in color (also know as rubor). Other inflammatory agents like leukotrienes, cytokines, and prostaglandins contribute to the inflammatory response, causing further vasodilation, pain, and broncoconstriction. Usually the allergic reaction is limited to the immediate area where the allergen made contact. Anaphylaxis is a severe, systemic allergic response, involving broncoconstriction and global vasodilation, which leads to difficulty breathing and shock. Anaphylaxis is a life-threatening emergency, but is treatable with prompt intervention. The allergic response to a drug may occur in several different ways (Type I, II, or III), and the signs and symptoms will vary depending on the mechanism and severity. Rash and itchiness are the most common presentations of a drug allergy.

The reason allergic reactions should not be confused with side effects is because of the outcome. An allergic reaction to a drug can be very dangerous, so it is important to avoid it by using alternative medications. Side effects are often unpleasant, but rarely immediately life-threatening. For instance, the flushing that occurs when taking niacin is not an immune hypersensitivity reaction, even though it appears as one. Opioids like hydrocodone or oxycodone may cause nausea, but not due to an allergic response. Additionally, almost all medications have side effects, so it is harder to pick and choose in that case. This is why healthcare workers ask for the reaction associated with an allergy; they are trying to distinguish a true allergy from an unpleasant side effect.

I have two points, one for healthcare professionals and one for the general public. First, if you are asking a patient about any drug allergies, be sure to ask for the type of reaction that occurs. It is reasonable that the average individual may not know the difference between a side affect and allergy, but the RN/MD/DO/PA/NP needs to know whether there are any contraindications to particular medications. Second, if you are telling a healthcare worker about an adverse drug reaction, be sure to mention what happens when you take it. Additionally, if you are unsure about whether or not you are allergic to a medication, be sure to ask (and write down the response for that matter).

Sources
1. Drug allergies. PubMed Health. 2010. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001822/. Accessed June 21, 2012.

2. Levinson W. Chapter 65. Hypersensitivity (Allergy). In: Levinson W, ed. Review of Medical Microbiology and Immunology. 11th ed. New York: McGraw-Hill; 2010. http://www.accessmedicine.com/content.aspx?aID=6459867. Accessed June 21, 2012.

3. Papaliodis D, Boucher W, Kempuraj D, Michaelian M, Wolfberg A, House M, Theoharide TC. Niacin-induced "flush" involves release of prostaglandin D2 from mast cells and serotonin from platelets: Evidence from human cells in vitro and an animal model. J Pharmacol Exp Ther. 2008;327:665-672.